Title : Specific differentiation events induced by erythropoietin in cells infected in vitro with the anemia strain of Friend virus.

Pub. Date : 1982 Jan

PMID : 6952215






1 Functional Relationships(s)
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1 Those events of erythroid differentiation shown to be directed by EP were extrusion of the nucleus from the erythroblast, induction of uroporphyrinogen I synthetase activity, increased iron incorporation into protoporphyrin, synthesis of alpha- and beta-globin polypeptides due largely to increased mRNA production, and synthesis and incorporation of spectrin into the cell membrane. Iron erythropoietin Mus musculus