Title : Regio- and stereoselective metabolism of two C19 steroids by five highly purified and reconstituted rat hepatic cytochrome P-450 isozymes.

Pub. Date : 1983 Jul 25

PMID : 6863312






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Regio- and stereoselective metabolism of two C19 steroids by five highly purified and reconstituted rat hepatic cytochrome P-450 isozymes. Steroids cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus
2 These results indicate that certain cytochrome P-450 isozymes show marked positional specificity in the metabolism of both testosterone and androstenedione, and that the rate as well as stereoselectivity of the oxidative reactions can be markedly dependent on subtle differences in the structure of the steroid substrate. Steroids cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus