Title : Hypothalamic integration of dopaminergic and opiate pathways controlling vasopressin secretion.

Pub. Date : 1983 Jul

PMID : 6861716






3 Functional Relationships(s)
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1 In control rats, morphine (50 micrograms) injected into the third ventricle resulted in a rapid increase in plasma vasopressin concentrations at 10 min, followed by a reduction at 20 min. Morphine arginine vasopressin Rattus norvegicus
2 The circumventricular organ-lesioned rats, however, showed a pronounced fall in vasopressin secretion both at 10 and 20 min after 50 micrograms morphine. Morphine arginine vasopressin Rattus norvegicus
3 A similar abolition of the morphine-elicited rise in plasma vasopressin could also be achieved by the iv infusion of small doses of dopamine in normal rats. Morphine arginine vasopressin Rattus norvegicus