Title : Partial inhibition of hepatic microsomal aminopyrine N-demethylase by caffeine in partially purified cytochrome P450.

Pub. Date : 1983 Mar 31

PMID : 6830852






1 Functional Relationships(s)
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1 Caffeine addition (in vitro) to partially purified cytochrome P-450 altered the hexobarbital, aniline and ethylisocyanide induced spectral change, and decreased NADPH oxidation in presence of substrates aminopyrine and acetanilide. Hexobarbital cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus