Title : Galactose 6-sulfate sulfatase activity in Morquio syndrome.

Pub. Date : 1982 Jul 1

PMID : 6809361






2 Functional Relationships(s)
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1 Our results could be explained by the hypothesis that accumulation of keratan sulfate and chondroitin 6-sulfate in Morquio syndrome is due to a deficiency of galactose 6-sulfate sulfatase and N-acetylgalactosamine 6-sulfate sulfatase activity, which are necessary for the degradation of these two mucopolysaccharides. Chondroitin Sulfates galactosamine (N-acetyl)-6-sulfatase Homo sapiens
2 Our results could be explained by the hypothesis that accumulation of keratan sulfate and chondroitin 6-sulfate in Morquio syndrome is due to a deficiency of galactose 6-sulfate sulfatase and N-acetylgalactosamine 6-sulfate sulfatase activity, which are necessary for the degradation of these two mucopolysaccharides. Chondroitin Sulfates galactosamine (N-acetyl)-6-sulfatase Homo sapiens