Title : A phorbol ester (TPA) can replace macrophages in human lymphocyte cultures stimulated with a mitogen but not with an antigen.

Pub. Date : 1982 Apr

PMID : 6801122






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The phorbol ester, 12-O-tetradecanoyl-phorbol-13-acetate (TPA), has been shown to have IL 1-like effects in other species and is a polyclonal activator of human T and B lymphocytes. Tetradecanoylphorbol Acetate interleukin 1 alpha Homo sapiens
2 The phorbol ester, 12-O-tetradecanoyl-phorbol-13-acetate (TPA), has been shown to have IL 1-like effects in other species and is a polyclonal activator of human T and B lymphocytes. Tetradecanoylphorbol Acetate interleukin 1 alpha Homo sapiens
3 Thus, TPA appears to mimic the macrophage-replacing ability of soluble factors (IL 1, macrophage supernatants) in the triggering of human lymphocytes. Tetradecanoylphorbol Acetate interleukin 1 alpha Homo sapiens