Title : Lysophosphatidic acid potentiates the thrombin-induced production of arachidonate metabolites in platelets.

Pub. Date : 1981 Dec 10

PMID : 6795196






2 Functional Relationships(s)
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1 Lysophosphatidic acid potentiates the thrombin-induced production of arachidonate metabolites in platelets. lysophosphatidic acid coagulation factor II, thrombin Homo sapiens
2 Concentrations (1 to 20 microM) of 1-oleoyl-lysophosphatidic acid which alone do not affect platelet metabolism of arachidonic acid, do augment the effects of suboptimal concentrations of thrombin on the formation of [14C]phosphatidic acid and the production of [14C]arachidonate metabolites from platelets prelabeled with [14C]arachidonate. lysophosphatidic acid coagulation factor II, thrombin Homo sapiens