Title : The use of human skin fibroblasts to obtain potency estimates of drug binding to androgen receptors.

Pub. Date : 1984 Jul

PMID : 6725525






1 Functional Relationships(s)
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1 Danazol, an androgen agonist that causes hirsutism, was nearly as effective as spironolactone in its ability to compete for the fibroblast androgen receptor, 50% inhibition of fibroblast [3H]DHT binding was achieved by 1.76 +/- 0.31 nM spironolactone and 2.85 +/- 0.50 nM danazol. Danazol androgen receptor Homo sapiens