Pub. Date : 1983 Oct 15
PMID : 6658711
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Partial reduction of thrombin disulfide bridges with dithiothreitol in the absence of denaturants inhibits the fibrinogen clotting but not the esterase activity of the enzyme. | Dithiothreitol | coagulation factor II, thrombin | Homo sapiens |
| 2 | As a result of the reaction with dithiothreitol, two disulfide bonds are cleaved in thrombin molecule inducing a small decrease of beta-sheets in the secondary structure of thrombin. | Dithiothreitol | coagulation factor II, thrombin | Homo sapiens |
| 3 | As a result of the reaction with dithiothreitol, two disulfide bonds are cleaved in thrombin molecule inducing a small decrease of beta-sheets in the secondary structure of thrombin. | Dithiothreitol | coagulation factor II, thrombin | Homo sapiens |