Title : Inhibition of mitochondrial oxidative metabolism by SKF-525A in intact cells and isolated mitochondria.

Pub. Date : 1983 Nov 15

PMID : 6651857






1 Functional Relationships(s)
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1 an uncoupling action at low concentrations (0.02 to 0.17 mM); at higher concentrations (0.2 to 0.5 mM) an inhibition of the oxidation of NAD(P)+-linked substrates, exerted close to the substrate level; also at 0.2 to 0.5 mM, a less effective inhibition of electron transfer at a point between cytochrome b and O2 in the electron-transfer chain. NADP mitochondrially encoded cytochrome b Homo sapiens