Title : Mechanism of furosemide-induced natriuresis by direct stimulation of renal prostaglandin E2.

Pub. Date : 1984 Oct

PMID : 6594069






2 Functional Relationships(s)
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1 Studies were conducted to investigate the interaction of renal prostaglandin E2 (PGE2) production and the renin-angiotensin system in the mechanism of furosemide-induced natriuresis. Furosemide LOW QUALITY PROTEIN: renin Oryctolagus cuniculus
2 In conscious rabbits with permanent urinary bladder cannulation, furosemide in vivo (10 mg/kg) increased urinary water, sodium, and PGE2 excretion and plasma renin activity (PRA) over 50 min. Furosemide LOW QUALITY PROTEIN: renin Oryctolagus cuniculus