Title : Inactivation of rat ovarian 20 alpha-hydroxysteroid dehydrogenase by N-alkylmaleimides.

Pub. Date : 1984 Sep

PMID : 6593001






1 Functional Relationships(s)
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1 A series of N-alkylmaleimides, varying in chain length from N-ethylmaleimide and N-butyl to N-octyl, inclusive, was shown to effectively inactivate rat ovarian 20 alpha-hydroxysteroid dehydrogenase at pH 7.7, 25 degrees C. The apparent second-order rate constants for inactivation were observed to increase with increasing chain length of the N-alkylmaleimide used. Ethylmaleimide aldo-keto reductase family 1, member C3 Rattus norvegicus