Title : Initiation of the alternative complement pathway due to spontaneous hydrolysis of the thioester of C3.

Pub. Date : 1983

PMID : 6586103






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 The product, C3(H2O), is functionally C3b-like and forms a C3 convertase with Factors B and D. The resulting biomolecular enzyme, C3(H2O),Bb, is a serine protease that cleaves C3 generating metastable C3b. Water complement C3 Homo sapiens
2 The product, C3(H2O), is functionally C3b-like and forms a C3 convertase with Factors B and D. The resulting biomolecular enzyme, C3(H2O),Bb, is a serine protease that cleaves C3 generating metastable C3b. Water complement C3 Homo sapiens
3 The product, C3(H2O), is functionally C3b-like and forms a C3 convertase with Factors B and D. The resulting biomolecular enzyme, C3(H2O),Bb, is a serine protease that cleaves C3 generating metastable C3b. Water complement C3 Homo sapiens
4 The product, C3(H2O), is functionally C3b-like and forms a C3 convertase with Factors B and D. The resulting biomolecular enzyme, C3(H2O),Bb, is a serine protease that cleaves C3 generating metastable C3b. Water complement C3 Homo sapiens
5 C3(H2O),Bb produces only three to five metastable C3b molecules per enzyme before being inactivated by regulatory proteins. Water complement C3 Homo sapiens