Title : Purification and some properties of L-glutamate decarboxylase from human brain.

Pub. Date : 1978 May

PMID : 658037






1 Functional Relationships(s)
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1 The analysis of the effects of various inhibitors of mouse brain glutamate decarboxylase on the human enzyme confirms the strong competitive inhibition caused by 3-mercaptopropionic acid (Ki = 2.7 x 10(-6) M) while the Ki values for allylglycine and chloride ion are 1.8 x 10(-2) M and 2.2 x 10(-2) M, respectively. 3-Mercaptopropionic Acid glutamate-ammonia ligase (glutamine synthetase) Mus musculus