Title : Binding and degradation studies on angiotensin II.

Pub. Date : 1984 Sep

PMID : 6498633






4 Functional Relationships(s)
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1 Autoradiography of thin layer chromatograms of 125I-labelled AII treated with microsomes showed the parent peak (Rf = 0.4-0.45) and a single major degradation product peak (Rf = 0.25-0.30), and [125I]NaI had an Rf value higher than both 125I-labelled AII and its degradation product. Iodine-125 angiotensinogen Rattus norvegicus
2 Autoradiography of thin layer chromatograms of 125I-labelled AII treated with microsomes showed the parent peak (Rf = 0.4-0.45) and a single major degradation product peak (Rf = 0.25-0.30), and [125I]NaI had an Rf value higher than both 125I-labelled AII and its degradation product. Iodine-125 angiotensinogen Rattus norvegicus
3 Autoradiography of thin layer chromatograms of 125I-labelled AII treated with microsomes showed the parent peak (Rf = 0.4-0.45) and a single major degradation product peak (Rf = 0.25-0.30), and [125I]NaI had an Rf value higher than both 125I-labelled AII and its degradation product. Iodine-125 angiotensinogen Rattus norvegicus
4 However, the degradation product neither showed specific binding to the microsomes nor interfered with the specific binding of 125I-labelled AII. Iodine-125 angiotensinogen Rattus norvegicus