Title : Inhibition of rat hepatic mixed function oxidases by antimalarial drugs: selectivity for cytochromes P-450 and P-448.

Pub. Date : 1984 Oct

PMID : 6488390






1 Functional Relationships(s)
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1 The N-demethylation of benzphetamine (cytochrome P-450) was inhibited by chloroquine only while the O-deethylation of ethoxyresorufin (cytochrome P-448) was inhibited by primaquine and quinacrine. ethoxyresorufin cytochrome P450, family 1, subfamily a, polypeptide 2 Rattus norvegicus