Pub. Date : 1984 Oct
PMID : 6480832
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | When the compound 5-amino-4-imidazolecarboxamide riboside (AICAriboside) is phosphorylated to the riboside monophosphate in the myocyte it is an inhibitor of adenylosuccinate lyase, one of the enzymes of the purine nucleotide cycle. | acadesine | adenylosuccinate lyase | Mus musculus |
| 2 | When the compound 5-amino-4-imidazolecarboxamide riboside (AICAriboside) is phosphorylated to the riboside monophosphate in the myocyte it is an inhibitor of adenylosuccinate lyase, one of the enzymes of the purine nucleotide cycle. | acadesine | adenylosuccinate lyase | Mus musculus |
| 3 | Disruption of the purine nucleotide cycle during muscle stimulation was evidenced by a greater accumulation of adenylosuccinate, the substrate for adenylosuccinate lyase, in the animals receiving AICAriboside (0.60 +/- 0.10 vs. 0.05 +/- 0.01 nmol/mumol total creatine, P less than 0.0001). | acadesine | adenylosuccinate lyase | Mus musculus |