Title : Some factors affecting the extraneuronal accumulation of adrenaline in guinea-pig trachealis smooth muscle cells.

Pub. Date : 1984 Jun

PMID : 6472500






1 Functional Relationships(s)
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1 Tracheal segments from guinea-pigs pretreated with 6-hydroxydopamine were incubated in 5 or 200 mumol X 1(-1) adrenaline at 37 degrees C. Catechol-O-methyltransferase and monoamine oxidase were inhibited by U-0521 and pargyline, respectively, and the accumulation of adrenaline in trachealis smooth muscle cells was measured by fluorescence microphotometry. Pargyline catechol O-methyltransferase Cavia porcellus