Title : Purification and characterization of a microsomal cytochrome P-450 with high activity of coumarin 7-hydroxylase from mouse liver.

Pub. Date : 1984 Nov 2

PMID : 6436023






2 Functional Relationships(s)
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1 Phenobarbital-induced coumarin 7-hydroxylase is high in DBA/2J and low in C57BL/6N inbred mice; this genetic difference is encoded by the Coh locus on chromosome 7. Phenobarbital cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus
2 P-450 fractions, highly specific for phenobarbital-inducible coumarin 7-hydroxylase activity, were purified from DBA/2J and C57BL/6N mouse liver microsomes. Phenobarbital cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus