Title : The impact of sulfonylurea treatment upon the mechanisms responsible for the insulin resistance in type II diabetes.

Pub. Date : 1984 May-Jun

PMID : 6376033






2 Functional Relationships(s)
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1 Thus, after 3 mo of glyburide treatment, glycemic control is markedly improved and this is accompanied by an increase in insulin secretion, no change in cellular insulin receptors, decreased hepatic glucose production rates, and an increase in overall insulin-mediated glucose disposal. Glyburide insulin Homo sapiens
2 After 18 mo of glyburide treatment, an increase in insulin secretion can no longer be demonstrated, whereas insulin binding to receptors is now significantly increased. Glyburide insulin Homo sapiens