Title : Age-related changes in aldehyde reductase activity of rat brain, liver and heart.

Pub. Date : 1984

PMID : 6373505






3 Functional Relationships(s)
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1 Aldehyde reductase (AR) activity was measured in the brain, liver and heart of 23- to 26-month-old and 3-month-old male Wistar rats, using 5 substrates (p-nitrobenzaldehyde, D-glucuronate, D-xylose, DL-glyceraldehyde and pyridine 3-aldehyde). Glucuronic Acid aldo-keto reductase family 1, member B7 Rattus norvegicus
2 A significant increase of AR activity was found in whole brain of old rats with p-nitrobenzaldehyde (11%) and D-glucuronate (24%). Glucuronic Acid aldo-keto reductase family 1, member B7 Rattus norvegicus
3 A significant increase of AR activity of old rats was also found in liver with D-glucuronate (10%), DL-glyceraldehyde (23%) and pyridine 3-aldehyde (30%), and in heart with p-nitrobenzaldehyde (42%) and DL-glyceraldehyde (20%). Glucuronic Acid aldo-keto reductase family 1, member B7 Rattus norvegicus