Pub. Date : 1978 Apr
PMID : 633081
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Responses of heart ornithine decarboxylase and adrenal catecholamines to methadone and sympathetic stimulants in developing and adults rats. | Methadone | ornithine decarboxylase 1 | Rattus norvegicus |
| 2 | Methadone administration to adult rats stimulated heart ODC, and this stimulation could be blocked by the sympatholytic agents chlorisondamine, reserpine or propranolol, suggesting that the effect is mediated via central stimulation of sympathetic nerves. | Methadone | ornithine decarboxylase 1 | Rattus norvegicus |
| 3 | With repeated methadone administration, tolerance developed to the heart ODC stimulation by methadone, eventually resulting in decreased heart ODC accompanied by deficits in heart weight. | Methadone | ornithine decarboxylase 1 | Rattus norvegicus |
| 4 | With repeated methadone administration, tolerance developed to the heart ODC stimulation by methadone, eventually resulting in decreased heart ODC accompanied by deficits in heart weight. | Methadone | ornithine decarboxylase 1 | Rattus norvegicus |
| 5 | With repeated methadone administration, tolerance developed to the heart ODC stimulation by methadone, eventually resulting in decreased heart ODC accompanied by deficits in heart weight. | Methadone | ornithine decarboxylase 1 | Rattus norvegicus |
| 6 | With repeated methadone administration, tolerance developed to the heart ODC stimulation by methadone, eventually resulting in decreased heart ODC accompanied by deficits in heart weight. | Methadone | ornithine decarboxylase 1 | Rattus norvegicus |
| 7 | The cardiac responses to nicotine developed somewhat differently, with significant ODC stimulation first appearing at 12 days in controls and at 8 days in methadone-treated pups. | Methadone | ornithine decarboxylase 1 | Rattus norvegicus |