Title : Cytoplasmic Ca2+ in platelets is controlled by cyclic AMP: antagonism between stimulators and inhibitors of adenylate cyclase.

Pub. Date : 1984 Apr 30

PMID : 6329175






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Stimulators of adenylate cyclase (i.e. PGI2, PGD2, forskolin) suppressed or reversed the increase of [Ca2+]i. Inhibitors of adenylate cyclase (i.e. epinephrine, ADP), added before or after thrombin, counteracted PGI2, PGD2 and forskolin and thereby increased [Ca2+]i and restored secretion. Colforsin coagulation factor II, thrombin Homo sapiens