Title : Role of pH as a transduction device in triggering electrical and secretory responses in islet B cells.

Pub. Date : 1984 Jun

PMID : 6327397






1 Functional Relationships(s)
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1 Regulation of pHi appears to occur by Na:H and HCO3:Cl exchange in the plasma membrane, because inhibition by 0.1 mM amiloride and 0.5 mM 4,4"-diisothiocyano-2,2"-stilbene disulfonic acid (DIDS), respectively, induces constant spike activity in the presence of 11.1 mM glucose. Bicarbonates glucose-6-phosphate isomerase Rattus norvegicus