Title : Failure of valproic acid to inhibit the growth of an ACTH-secreting pituitary adenoma.

Pub. Date : 1984 Apr

PMID : 6326445






4 Functional Relationships(s)
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1 Di-n-propylacetic acid (valproic acid) has been reported to lower plasma ACTH concentration after both acute and chronic administration of the drug. Valproic Acid proopiomelanocortin Homo sapiens
2 Di-n-propylacetic acid (valproic acid) has been reported to lower plasma ACTH concentration after both acute and chronic administration of the drug. Valproic Acid proopiomelanocortin Homo sapiens
3 Despite a lowering of her plasma ACTH concentration during therapy with valproic acid, the patient"s tumour showed no evidence of regression while she was taking the drug. Valproic Acid proopiomelanocortin Homo sapiens
4 In view of these findings, valproic acid therapy for ACTH-secreting pituitary tumours needs to be re-evaluated. Valproic Acid proopiomelanocortin Homo sapiens