Title : Effect of PTH and 1,25(OH)2D3 on renal 25(OH)D3 metabolism, adenylate cyclase, and protein kinase.

Pub. Date : 1984 Jan

PMID : 6320659






4 Functional Relationships(s)
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1 Effect of PTH and 1,25(OH)2D3 on renal 25(OH)D3 metabolism, adenylate cyclase, and protein kinase. Calcifediol parathyroid hormone Rattus norvegicus
2 The purpose of these studies was to characterize the action of PTH and 1,25(OH)2D3 on the renal metabolism of 25(OH)D3 to 1,25(OH)2D3 and 24,25(OH)2D3. Calcifediol parathyroid hormone Rattus norvegicus
3 1,25(OH)2D3 also blocked the effect of PTH (5.0 U/ml) on renal 25(OH)D3 metabolism. Calcifediol parathyroid hormone Rattus norvegicus
4 These studies demonstrate that PTH may act directly on the kidney to modulate renal 25(OH)D3 metabolism and that this action can be inhibited by 1,25(OH)2D3. Calcifediol parathyroid hormone Rattus norvegicus