Title : Increased sensitivity of gastrin release to adrenaline in duodenal ulcer.

Pub. Date : 1978 Mar

PMID : 631642






9 Functional Relationships(s)
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1 Increased sensitivity of gastrin release to adrenaline in duodenal ulcer. Epinephrine gastrin Homo sapiens
2 The maximal rise in serum gastrin concentrations was obtained at a dose of 4 microgram/min adrenaline in both groups of subjects, and the increase was significantly higher in duodenal ulcer patients than in controls. Epinephrine gastrin Homo sapiens
3 Adrenaline increased predominantly the gastrin III component (gastrin-17 like) in both duodenal ulcer patients and controls. Epinephrine gastrin Homo sapiens
4 Adrenaline increased predominantly the gastrin III component (gastrin-17 like) in both duodenal ulcer patients and controls. Epinephrine gastrin Homo sapiens
5 The threshold level of adrenaline-induced gastrin release was significantly lower in duodenal ulcer patients: intravenous infusion of adrenaline in a dose of 0.12 microgram and 0.25 microgram/min increased serum gastrin concentrations 23 and 43%, respectively, but had no effect in controls. Epinephrine gastrin Homo sapiens
6 The threshold level of adrenaline-induced gastrin release was significantly lower in duodenal ulcer patients: intravenous infusion of adrenaline in a dose of 0.12 microgram and 0.25 microgram/min increased serum gastrin concentrations 23 and 43%, respectively, but had no effect in controls. Epinephrine gastrin Homo sapiens
7 The threshold level of adrenaline-induced gastrin release was significantly lower in duodenal ulcer patients: intravenous infusion of adrenaline in a dose of 0.12 microgram and 0.25 microgram/min increased serum gastrin concentrations 23 and 43%, respectively, but had no effect in controls. Epinephrine gastrin Homo sapiens
8 The threshold level of adrenaline-induced gastrin release was significantly lower in duodenal ulcer patients: intravenous infusion of adrenaline in a dose of 0.12 microgram and 0.25 microgram/min increased serum gastrin concentrations 23 and 43%, respectively, but had no effect in controls. Epinephrine gastrin Homo sapiens
9 The results indicate that endogenous adrenaline may stimulate the secretion of gastrin during physiological conditions in patients with duodenal ulcer. Epinephrine gastrin Homo sapiens