Pub. Date : 1983 Oct
PMID : 6315672
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Influence of clindamycin on fibronectin-staphylococcal interactions. | Clindamycin | fibronectin 1 | Homo sapiens |
| 2 | This report examines the effects of subinhibitory concentrations of of clindamycin on fibronectin-staphylococcal interactions. | Clindamycin | fibronectin 1 | Homo sapiens |
| 3 | Using in-vitro binding assays, exposure of staphylococci to subinhibitory concentrations of clindamycin results in a dose-dependent decrease in fibronectin"s ability to bind to treated organisms. | Clindamycin | fibronectin 1 | Homo sapiens |
| 4 | Serum-mediated phagocytosis of clindamycin-treated organisms remained effective despite the reduction in fibronectin binding capabilities. | Clindamycin | fibronectin 1 | Homo sapiens |
| 5 | These results suggest that the clinical use of clindamycin has the potential to affect bacterial binding of fibronectin, thus modifying the adherence of organisms to host surfaces without adversely effecting their clearance by the reticuloendothelial system. | Clindamycin | fibronectin 1 | Homo sapiens |