Title : Biochemical cascade mediating the estradiol action.

Pub. Date : 1983 Aug

PMID : 6313401






1 Functional Relationships(s)
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1 The data suggest that estradiol enhances the formation of histamine in rat uterus by induction of histidine decarboxylase; histamine activates adenylate cyclase providing accumulation of cyclic 3",5"-AMP, which, probably, induces glycolytic enzymes via phosphorylation of chromatin proteins, and mediates other estradiol effects. Histamine histidine decarboxylase Rattus norvegicus