Title : Genetic differences in metabolism of benzo(a)pyrene in cultured epidermal and dermal cells of responsive and nonresponsive mice.

Pub. Date : 1983 Aug

PMID : 6305490






2 Functional Relationships(s)
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1 In the epidermal cells, basal AHH activity varied within a relatively small range of 4.6 to 8.8 pmol per mg protein per hr, and the activity was increased 4.4 to 8.7 times by benz(a)anthracene treatment. anthracene cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus
2 In dermal cells, the basal level of AHH activity was in the range of 3.6 to 9.1 pmol per mg protein per hr, and benz(a)anthracene treatment induced AHH, but to various degrees depending on the responsiveness in vivo. anthracene cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus