Title : Role of calcium and prostaglandins in the antidiuretic hormone response. Effect of ionophore A23187.

Pub. Date : 1983 Mar 15

PMID : 6301507






3 Functional Relationships(s)
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1 Role of calcium and prostaglandins in the antidiuretic hormone response. Prostaglandins arginine vasopressin Homo sapiens
2 Indomethacin, a prostaglandin synthesis inhibitor, prevented the inhibitory actions of the IP on the ADH-mediated response. Prostaglandins arginine vasopressin Homo sapiens
3 Collectively, these observations suggest a key role for cellular calcium in modulating the actions of antidiuretic hormone and are consistent with the hypothesis that the ionophore, through increasing intracellular calcium, stimulates the synthesis of prostaglandins which have a negative feedback on adenylcyclase. Prostaglandins arginine vasopressin Homo sapiens