Title : Characteristics of microsomal reduction of benzo[a]pyrene 4,5-oxide.

Pub. Date : 1982 Jul 1

PMID : 6282475






1 Functional Relationships(s)
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1 NADPH-reduction of benzo[a]pyrene 4,5-oxide (BP-4,5-oxide) to BP required four components from rat liver: cytochrome P-450, NADPH cytochrome P-450 reductase, phosphatidylcholine and a soluble, heat-sensitive factor which was present in 105 000 X g supernatant and was also released from microsomes by sonication. NADP cytochrome p450 oxidoreductase Rattus norvegicus