Title : Role of catalase and hydroxyl radicals in the oxidation of methanol by rat liver microsomes.

Pub. Date : 1982 Feb 1

PMID : 6280725






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In the absence of the catalase inhibitor azide, methanol may be oxidized primarily by the peroxidatic activity of catalase since there was little effect on methanol oxidation by competing hydroxyl radical scavengers. Hydroxyl Radical catalase Rattus norvegicus
2 The azide-insensitive (catalase-independent) pathway of methanol oxidation was inhibited by scavengers of hydroxyl radicals. Hydroxyl Radical catalase Rattus norvegicus
3 The stimulation by iron-EDTA was blocked by the competing hydroxyl radical scavengers even in the absence of azide, suggesting that the added iron-EDTA favorably with microsomal catalase for H2O2 to produce hydroxyl radicals (or a species with the oxidizing power of the hydroxyl radical). Hydroxyl Radical catalase Rattus norvegicus
4 The stimulation by iron-EDTA was blocked by the competing hydroxyl radical scavengers even in the absence of azide, suggesting that the added iron-EDTA favorably with microsomal catalase for H2O2 to produce hydroxyl radicals (or a species with the oxidizing power of the hydroxyl radical). Hydroxyl Radical catalase Rattus norvegicus
5 The stimulation by iron-EDTA was blocked by the competing hydroxyl radical scavengers even in the absence of azide, suggesting that the added iron-EDTA favorably with microsomal catalase for H2O2 to produce hydroxyl radicals (or a species with the oxidizing power of the hydroxyl radical). Hydroxyl Radical catalase Rattus norvegicus