Title : Suppression of luteinizing hormone and testosterone secretion in bulls following adrenocorticotropin hormone treatment.

Pub. Date : 1982 Mar

PMID : 6279191






5 Functional Relationships(s)
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1 dose of adrenocorticotropic hormone (ACTH; 80 IU) resulted in a corticosteroid peak which lasted approximately 6 h. During this 6 h period, no episodic increases in secretion of LH or testosterone were initiated and basal concentrations of testosterone were suppressed (P less than 0.05) below control values. Testosterone proopiomelanocortin Homo sapiens
2 dose of adrenocorticotropic hormone (ACTH; 80 IU) resulted in a corticosteroid peak which lasted approximately 6 h. During this 6 h period, no episodic increases in secretion of LH or testosterone were initiated and basal concentrations of testosterone were suppressed (P less than 0.05) below control values. Testosterone proopiomelanocortin Homo sapiens
3 dose of adrenocorticotropic hormone (ACTH; 80 IU) resulted in a corticosteroid peak which lasted approximately 6 h. During this 6 h period, no episodic increases in secretion of LH or testosterone were initiated and basal concentrations of testosterone were suppressed (P less than 0.05) below control values. Testosterone proopiomelanocortin Homo sapiens
4 Episodic secretion of LH and testosterone resumed 6--7 h after ACTH when concentrations of serum corticosteroids had returned to basal levels. Testosterone proopiomelanocortin Homo sapiens
5 These results suggest that ACTH-induced increases in serum corticosteroids suppress the episodic secretion of LH, resulting in a suppression of testosterone secretion by the bull testis. Testosterone proopiomelanocortin Homo sapiens