Title : A study of desensitization of acetylcholine receptors using nerve-released transmitter in the frog.

Pub. Date : 1981 Jul

PMID : 6275065






1 Functional Relationships(s)
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1 When the acetylcholinesterase was inhibited with diisopropylfluorophosphate, neostigmine, or collagenase treatment to prolong the duration of the nerve-released ACh in the synaptic cleft, desensitization developed during repetitive stimulation of 1000 impulses at 5-33 impulses/sec and then recovered after the conditioning trains, with a time constant of about 25 sec.4. Isoflurophate acetylcholinesterase (Cartwright blood group) Homo sapiens