Pub. Date : 1981 Nov
PMID : 6272977
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | These studies suggest that the microsomal metabolism of benzo(a)pyrene (BP) produces metabolites which can be methylated by the catechol-o-methyltransferase (COMT)/S-adenosylmethionine (SAM) enzyme/donor combination. | Benzo(a)pyrene | catechol-O-methyltransferase | Homo sapiens |
| 2 | These studies suggest that the microsomal metabolism of benzo(a)pyrene (BP) produces metabolites which can be methylated by the catechol-o-methyltransferase (COMT)/S-adenosylmethionine (SAM) enzyme/donor combination. | Benzo(a)pyrene | catechol-O-methyltransferase | Homo sapiens |
| 3 | These studies suggest that the microsomal metabolism of benzo(a)pyrene (BP) produces metabolites which can be methylated by the catechol-o-methyltransferase (COMT)/S-adenosylmethionine (SAM) enzyme/donor combination. | Benzo(a)pyrene | catechol-O-methyltransferase | Homo sapiens |
| 4 | These studies suggest that the microsomal metabolism of benzo(a)pyrene (BP) produces metabolites which can be methylated by the catechol-o-methyltransferase (COMT)/S-adenosylmethionine (SAM) enzyme/donor combination. | Benzo(a)pyrene | catechol-O-methyltransferase | Homo sapiens |
| 5 | Approximately 0.06% of substrate BP was recovered as COMT/SAM-reactive substances. | Benzo(a)pyrene | catechol-O-methyltransferase | Homo sapiens |
| 6 | Organic extracts of COMT/[14C]SAM incubations with BP were fractionated by high-performance liquid chromatography. | Benzo(a)pyrene | catechol-O-methyltransferase | Homo sapiens |
| 7 | When the Ames mutagenesis assay was supplemented with COMT/SAM, a 36% reduction was observed in the number of revertant colonies induced by the microsomal oxidation of BP. | Benzo(a)pyrene | catechol-O-methyltransferase | Homo sapiens |