Pub. Date : 1980 Aug
PMID : 6248808
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sites at which clonidine acts to affect blood pressure and the secretion of renin, growth hormone and ACTH. | Clonidine | renin | Canis lupus familiaris |
| 2 | To further define the sites in the brain at which clonidine acts to lower blood pressure, inhibit renin secretion, inhibit ACTH secretion, and stimulate growth hormone secretion, small doses of this drug were infused into the vertebral arteries, into the carotid arteries and intravenously in pentobarbital-anesthetized dogs. | Clonidine | renin | Canis lupus familiaris |
| 3 | Intracarotid and intravertebral clonidine decreased plasma renin activity whereas in this dose intravenous clonidine did not. | Clonidine | renin | Canis lupus familiaris |
| 4 | The data confirm the observation that clonidine acts on the brain to inhibit renin secretion, and establish that the renin-inhibiting site is different from the blood pressure-lowering site. | Clonidine | renin | Canis lupus familiaris |