Title : Spin-trapping and direct electron spin resonance investigations of the redox metabolism of quinone anticancer drugs.

Pub. Date : 1980 Jun 5

PMID : 6248123






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The superoxide free radical has been spin trapped in microsomal incubations containing adriamycin, daunorubicin, and mitomycin C. Superoxides spindlin 1 Homo sapiens
2 The time sequence of the appearance of the spin-trapped superoxide and the semiquinone radical metabolite of these quinone-containing anticancer drugs indicates that air oxidation of the semiquinone is responsible for the superoxide formation. Superoxides spindlin 1 Homo sapiens
3 The time sequence of the appearance of the spin-trapped superoxide and the semiquinone radical metabolite of these quinone-containing anticancer drugs indicates that air oxidation of the semiquinone is responsible for the superoxide formation. Superoxides spindlin 1 Homo sapiens
4 Superoxide dismutase prevents the formation of the superoxide spin adducts. Superoxides spindlin 1 Homo sapiens