Title : Changes in circulating androgens during short term carbamazepine therapy.

Pub. Date : 1984 Mar

PMID : 6231939






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Within 7 days of starting CBZ there was a rise in SHBG (P less than 0.05) and a fall in testosterone, free testosterone fraction, DHAS and androstenedione (P less than 0.05). Carbamazepine sex hormone binding globulin Homo sapiens
2 The rise in SHBG and increased androgen catabolism is most likely to be secondary to induction of hepatic monooxygenase activity by CBZ. Carbamazepine sex hormone binding globulin Homo sapiens