Title : Effects of diethyldithiocarbamate and nine other nucleophiles on the intersubunit protein cross-linking and inactivation of purified human alpha 2-macroglobulin by cis-diamminedichloroplatinum(II).

Pub. Date : 1984 Dec

PMID : 6209003






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Only KCN was comparably effective as an inhibitor of the reaction of cisplatin with alpha 2-macroglobulin; however, KCN was significantly less reactive with preformed platinum(II)-protein bonds than was diethyldithiocarbamate. Potassium Cyanide alpha-2-macroglobulin Homo sapiens