Title : Characteristics of basophil histamine release by neuromuscular blocking drugs in patients with anaphylactoid reactions.

Pub. Date : 1984 Apr

PMID : 6203365






1 Functional Relationships(s)
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1 The findings strongly suggest a non-cytotoxic secretory process requiring the presence of two quaternary ammonium groups as suggested by the rarity of release with tubocurarine; inhibition of succinyldicholine (suxamethonium)-induced histamine release by serum cholinesterase treatment, acetylcholine and tubocurarine; and the bell-shaped dose-response curve, particularly with suxamethonium. quaternary ammonium butyrylcholinesterase Homo sapiens