Title : Effects of 5-azacytidine on methylation and expression of specific DNA sequences in C3H 10T1/2 cells.

Pub. Date : 1984 Apr

PMID : 6201721






1 Functional Relationships(s)
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1 The present study indicates that the transient exposure of C3H 10T1/2 mouse embryo fibroblasts to 5-azacytidine leads to extensive loss of methylation of the protooncogene c-mos and the beta-globin locus at the cell population level and in at least 40 isolated subclones. Azacitidine Moloney sarcoma oncogene Mus musculus