Pub. Date : 1983 Dec
PMID : 6196380
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Localization of 131I-labeled p97-specific Fab fragments in human melanoma as a basis for radiotherapy. | Iodine-131 | FA complementation group B | Homo sapiens |
| 2 | 33 patients with advanced malignant melanoma were studied after intravenous administration of 131I-labeled Fab fragments specific for p97, an oncofetal glycoprotein of human melanoma. | Iodine-131 | FA complementation group B | Homo sapiens |
| 3 | Also, imaging studies of the bio-distribution of 131I-labeled anti-p97 Fab in patients selected for high p97 tumor concentration showed avid tumor uptake and more prolonged retention of labeled Fab in tumor than in normal tissues. | Iodine-131 | FA complementation group B | Homo sapiens |
| 4 | Also, imaging studies of the bio-distribution of 131I-labeled anti-p97 Fab in patients selected for high p97 tumor concentration showed avid tumor uptake and more prolonged retention of labeled Fab in tumor than in normal tissues. | Iodine-131 | FA complementation group B | Homo sapiens |
| 5 | For improved radiation safety, we developed automated methods to label Fab fragments with up to 200 mCi of 131I. | Iodine-131 | FA complementation group B | Homo sapiens |
| 6 | In two of these patients it was possible to successfully reinfuse after immunity had developed with 131I-(anti-p97) Fab of a different isotype (IgG2a). | Iodine-131 | FA complementation group B | Homo sapiens |