Pub. Date : 1983 Nov
PMID : 6193871
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Bleomycin, vincristine, or mitomycin C, when added to HeLa cells simultaneously with human fibroblast interferon (IFN-beta), caused a decrease in cell density and inhibited DNA synthesis compared with HeLa cells treated with IFN-beta alone. | Bleomycin | interferon beta 1 | Homo sapiens |
| 2 | Bleomycin, vincristine, or mitomycin C, when added to HeLa cells simultaneously with human fibroblast interferon (IFN-beta), caused a decrease in cell density and inhibited DNA synthesis compared with HeLa cells treated with IFN-beta alone. | Bleomycin | interferon beta 1 | Homo sapiens |
| 3 | HeLa cells treated with IFN-beta alone or with IFN-beta in combination with bleomycin, vincristine, or mitomycin C were able to induce the double-stranded RNA-dependent adenosine triphosphate:2",5"-oligoadenylic acid adenyltransferase (EC 2.2.2.-) and the double-stranded RNA-dependent protein kinase. | Bleomycin | interferon beta 1 | Homo sapiens |
| 4 | HeLa cells treated with IFN-beta alone or with IFN-beta in combination with bleomycin, vincristine, or mitomycin C were able to induce the double-stranded RNA-dependent adenosine triphosphate:2",5"-oligoadenylic acid adenyltransferase (EC 2.2.2.-) and the double-stranded RNA-dependent protein kinase. | Bleomycin | interferon beta 1 | Homo sapiens |
| 5 | These results indicate that, under these experimental conditions, the double-stranded RNA-dependent adenosine triphosphate:2",5"-oligoadenylic acid adenyltransferase and protein kinase can be induced by IFN-beta in cells treated with bleomycin, vincristine, or mitomycin C. | Bleomycin | interferon beta 1 | Homo sapiens |
| 6 | The possibility that IFN-beta potentiates the cytotoxic effects of bleomycin and mitomycin C on HeLa cells is also discussed. | Bleomycin | interferon beta 1 | Homo sapiens |