Title : Human interferon action: reciprocal regulation by retinoic acid and beta-carotene.

Pub. Date : 1983 May

PMID : 6188873






8 Functional Relationships(s)
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1 Thus retinoic acid (and retinol) inhibited the stimulatory action of interferon (IFN) on monocyte membrane function, and this inhibition was reversed by beta-carotene; beta-carotene alone modestly potentiated IFN in this system. Tretinoin interferon alpha 1 Homo sapiens
2 Thus retinoic acid (and retinol) inhibited the stimulatory action of interferon (IFN) on monocyte membrane function, and this inhibition was reversed by beta-carotene; beta-carotene alone modestly potentiated IFN in this system. Tretinoin interferon alpha 1 Homo sapiens
3 Remarkably, for the inhibitory action of IFN on lymphoblastoid cell division, the converse was true: beta-Carotene inhibited the cytostatic action of IFN, and this inhibition was reversed by retinoic acid; retinoic acid alone modestly potentiated IFN in this system. Tretinoin interferon alpha 1 Homo sapiens
4 Remarkably, for the inhibitory action of IFN on lymphoblastoid cell division, the converse was true: beta-Carotene inhibited the cytostatic action of IFN, and this inhibition was reversed by retinoic acid; retinoic acid alone modestly potentiated IFN in this system. Tretinoin interferon alpha 1 Homo sapiens
5 Remarkably, for the inhibitory action of IFN on lymphoblastoid cell division, the converse was true: beta-Carotene inhibited the cytostatic action of IFN, and this inhibition was reversed by retinoic acid; retinoic acid alone modestly potentiated IFN in this system. Tretinoin interferon alpha 1 Homo sapiens
6 Remarkably, for the inhibitory action of IFN on lymphoblastoid cell division, the converse was true: beta-Carotene inhibited the cytostatic action of IFN, and this inhibition was reversed by retinoic acid; retinoic acid alone modestly potentiated IFN in this system. Tretinoin interferon alpha 1 Homo sapiens
7 Remarkably, for the inhibitory action of IFN on lymphoblastoid cell division, the converse was true: beta-Carotene inhibited the cytostatic action of IFN, and this inhibition was reversed by retinoic acid; retinoic acid alone modestly potentiated IFN in this system. Tretinoin interferon alpha 1 Homo sapiens
8 Remarkably, for the inhibitory action of IFN on lymphoblastoid cell division, the converse was true: beta-Carotene inhibited the cytostatic action of IFN, and this inhibition was reversed by retinoic acid; retinoic acid alone modestly potentiated IFN in this system. Tretinoin interferon alpha 1 Homo sapiens