Title : The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells.

Pub. Date : 1982 Oct 25

PMID : 6181068






1 Functional Relationships(s)
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1 The two-electron reduction of quinones to diols, mediated by DT-diaphorase (NAD(P)H: (quinone-acceptor) oxidoreductase), may therefore represent a detoxifying pathway which protects the cell from the formation of these reactive intermediates. diols NAD(P)H quinone dehydrogenase 1 Homo sapiens