Pub. Date : 1982 Mar
PMID : 6173426
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Co-precipitation experiments show that antigenic determinants recognized by these two antibodies reside on the same molecular species, termed Mac-2, Mac-2, an antigen of 32,000 Mr, is synthesized by and expressed on the surface of thioglycollate-elicited macrophages as shown by [35S]-methionine and 125I labeling. | Thioglycolates | lectin, galactose binding, soluble 3 | Mus musculus |
| 2 | Co-precipitation experiments show that antigenic determinants recognized by these two antibodies reside on the same molecular species, termed Mac-2, Mac-2, an antigen of 32,000 Mr, is synthesized by and expressed on the surface of thioglycollate-elicited macrophages as shown by [35S]-methionine and 125I labeling. | Thioglycolates | lectin, galactose binding, soluble 3 | Mus musculus |
| 3 | Saturation binding experiments show that thioglycollate-elicited macrophages express 1.7 X 10(5) Mac-2 sites/cell. | Thioglycolates | lectin, galactose binding, soluble 3 | Mus musculus |
| 4 | In contrast, thioglycollate-elicited macrophages are greater than 96% strongly positive for Mac-2. | Thioglycolates | lectin, galactose binding, soluble 3 | Mus musculus |
| 5 | SDS-PAGE of [35S]-methionine-labeled Mac-2 shows that thioglycollate-elicited macrophages synthesize 10- to 30-fold more Mac-2 than other peritoneal macrophage subpopulations, whereas all types of peritoneal macrophages synthesize and express on their surfaces similar amounts of the Mac-1 antigen. | Thioglycolates | lectin, galactose binding, soluble 3 | Mus musculus |
| 6 | SDS-PAGE of [35S]-methionine-labeled Mac-2 shows that thioglycollate-elicited macrophages synthesize 10- to 30-fold more Mac-2 than other peritoneal macrophage subpopulations, whereas all types of peritoneal macrophages synthesize and express on their surfaces similar amounts of the Mac-1 antigen. | Thioglycolates | lectin, galactose binding, soluble 3 | Mus musculus |