Title : Acute and chronic treatment of severe and malignant hypertension with the oral angiotensin-converting enzyme inhibitor captopril.

Pub. Date : 1981 Oct

PMID : 6168412






2 Functional Relationships(s)
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1 Captopril acutely reduced blood pressure in all patients except two who had suppressed plasma renin activity. Captopril renin Homo sapiens
2 The maximal antihypertensive effect of captopril with or without diuretics was evident after 3 months of continuous therapy and was associated with elevated plasma renin levels, normal aldosterone excretion and preservation of renal function. Captopril renin Homo sapiens