Title : [Histamine-release: present data and practical interest (author's transl)].

Pub. Date : 1980

PMID : 6160567






1 Functional Relationships(s)
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1 The authors recall the innermost mechanism of the main stages of histamine-release: recognition of membrane receptors, multiple enzymatic activations, opening of calcic membrane pores, synthesis of unpreformed mediators (SRSa and PAF), finally granular extrusion with release of histamine and of numerous mediators, among which the neutrophil chemotactic factor, one of the main responsible ones of the late phase of hypersensitivity phenomena. Histamine PCNA clamp associated factor Homo sapiens