Title : Primary amines inhibit recycling of alpha 2M receptors in fibroblasts.

Pub. Date : 1980 May

PMID : 6156003






3 Functional Relationships(s)
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Protein Name
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1 Primary amines inhibit recycling of alpha 2M receptors in fibroblasts. Amines alpha-2-macroglobulin Homo sapiens
2 Receptor-mediated endocytosis of alpha 2M-protease complexes by normal human skin fibroblasts in culture was inhibited by the primary amines, methylamine and mono-dansylcadaverine. Amines alpha-2-macroglobulin Homo sapiens
3 We postulate that the primary amines, methylamine and mono-dansylcadaverine, interfere with the recycling of alpha 2M receptors, while the chemical nature of the amines and the conditions under which inhibition becomes apparent point to the involvement of transglutaminase in this recycling. Amines alpha-2-macroglobulin Homo sapiens